منابع مشابه
Leydig cell testicular tumors: About a case report
52-year-old patient, epileptic, consulted for isolated left testicular pain since three months. On examination, the left testicle was the seat of a small lower polar nodule of approximately 1 cm in size. No other sign, including gynecomastia or swelling of superficial lymph nodes was observed. Tumor markers such as alphafetoprotein (AFP), b-human chorionic gonadotropin (b-HCG) and lactate dehyd...
متن کاملApparent lack of immunogenicity of estrogen-induced testicular Leydig cell tumors in BALB/c mice.
Evaluating four in vivo indicators of immune response, we attempted to demonstrate immunogenic properties in transplantable malignant Leydig cell tumors (LCT) induced in BALB/c mice by chronic estrogen administration. Growing LCT failed to elicit the production either of the lymphokine migration inhibition factor by host splenocytes or of circulating antibodies detectable by indirect immunofluo...
متن کاملPrimary testicular abnormalities causing precocious puberty Leydig cell tumor, Leydig cell hyperplasia, and adrenal rest tumor.
The child with testicular enlargement in the absence of gonadotrophin stimulation presents a difficult diagnostic dilemma. Leydig cell tumors, Leydig cell hyperplasia, and tumors of adrenal rest tissue are the primary etiologic considerations. Because of considerable overlap in clinical presentation, careful biochemical and histologic evaluations are necessary to make the diagnosis. These shoul...
متن کاملHuman Relevance of Rodent Leydig Cell Tumors
Rodents have been used extensively in virtually all fields of biomedical research and have been the primary species used in toxicologic and carcinogenic research. Over many years it has become obvious that some conditions and in particular some tumors in rodents have questionable relevance in humans. Some of these include peroxisome proliferatoractivator receptor-α (PPAR-α) agonist-induced live...
متن کاملLeydig cell tumors of the testis.
Leydig cell tumors represent approximately one to three percent of all testicular tumors. Whereas in experimental animals predisposing conditions include administration of chemical carcinogens, hormones and heavy metals, environmental or endogenous factors in man are presently unrecognized. Leydig cell tumors do not show preferential lateralization or tendency for bilaterality. The symptoms are...
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ژورنال
عنوان ژورنال: European Urology Open Science
سال: 2020
ISSN: 2666-1683
DOI: 10.1016/s2666-1683(20)36270-4